ABSTRACT
No abstract available.
Subject(s)
Humans , Adenocarcinoma, Follicular/complications , Adenoma/complications , Biomarkers/blood , Calcium/blood , Hyperparathyroidism, Primary/blood , Parathyroid Hormone/blood , Parathyroid Neoplasms/complications , Predictive Value of Tests , Radiopharmaceuticals , Reproducibility of Results , Technetium Tc 99m Sestamibi , Thyroid Neoplasms/complications , ThyroidectomySubject(s)
Adenocarcinoma, Follicular/complications , Adenocarcinoma, Follicular/diagnosis , Adenocarcinoma, Follicular/pathology , Adenoma/complications , Adenoma/diagnosis , Adenoma/pathology , Carcinoma/complications , Carcinoma/diagnosis , Carcinoma/pathology , Carcinoma, Papillary/complications , Carcinoma, Papillary/diagnosis , Carcinoma, Papillary/pathology , Humans , Thyroid Gland/pathology , Thyroid Neoplasms/diagnosis , Thyroid Neoplasms/pathologyABSTRACT
A associação entre carcinoma diferenciado de tireoide (CDT) e tireoidite linfocitária crônica (TLC) tem sido relatada na literatura. OBJETIVO: Avaliar a incidência desta associação e determinar se a TLC pode influenciar no estadiamento tumoral do CDT quando associada a outras variáveis de risco. FORMA DE ESTUDO: Coorte histórica (retrospectiva). MATERIAL E MÉTODO: Avaliaram-se 52 prontuários e laudos de pacientes portadores de CDT, no período de 1999 a 2009, divididos em dois grupos. O primeiro, composto de 35 pacientes portadores de CDT sem TLC; o segundo, com 17 pacientes, associado à TLC. O tratamento instituído para todos os pacientes foi a tireoidectomia total. Variáveis comuns a ambos os grupos como idade, gênero, padrão histológico, diâmetro tumoral, metástase locorregional e à distância, invasão extratireoidiana, multifocalidade e presença de cápsula tumoral foram comparadas. Aplicou-se os testes t-Student e Qui-quadrado para análise dos dados. RESULTADOS: A incidência de CDT isolado foi maior do que a de CDT+TLC (p=0,0126). Nenhuma diferença estatística quanto às variáveis comuns analisadas foi observada. CONCLUSÕES: A presença de TLC ocorreu em 33 por cento dos pacientes com CDT. Todos os casos de CDT eram em estádios iniciais.
The association between differentiated thyroid carcinoma (DTC) and chronic lymphocytic thyroiditis (CLT) has been reported in literature. AIM: To evaluate the incidence of this association and to determine whether the CLT may influence on the early initial staging of DTC when associated with other variable risks. STUDY DESIGN: Historical (retrospective) cohort. MATERIALS AND METHODS: Fifty two patients with DTC were evaluated from 1999 to 2009. They were divided into two groups. The first group had 35 patients with DTC without DLT; the second had 17 patients with CLT. Total thyroidectomy was the treatment chosen for all patients. Similarities shared in both groups such as age, gender, histological tumor type, tumor diameter, regional only or with distant metastases, extrathyroidal invasion, multifocality and presence of tumor capsule were considered. T-Student tests and Chi-square tests were applied to analyze the data. RESULTS: The incidence of DTC without CLT was higher that of DTC+CLT (p=0.0126). We noticed no statistic differences between the common variables analyzed. CONCLUSIONS: CLT occurred in 33 percent of the patients with DCT. All cases of DTC were in the early stages.
Subject(s)
Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Young Adult , Adenocarcinoma, Follicular/pathology , Carcinoma, Papillary/pathology , Hashimoto Disease/complications , Thyroid Neoplasms/pathology , Adenocarcinoma, Follicular/complications , Cohort Studies , Carcinoma, Papillary/complications , Hashimoto Disease/pathology , Neoplasm Staging , Retrospective Studies , Thyroid Neoplasms/complicationsABSTRACT
In April 2006, a 55-year-old female presented with a thyroid mass and multiple skin nodules on scalp, forehead and neck. Fine needle aspiration cytology of thyroid mass and multiple skin nodules show tumor cells clusters in a repetitive microfollicular pattern on May-Grunwald-Giemsa stain suggestive of follicular thyroid carcinoma with metastasis to skin. Although follicular carcinoma have a propensity for vascular invasion and hematogenous dissemination, skin is not commonly involved. Only a few cases of cutaneous metastasis from follicular thyroid carcinoma are reported in the English language literature.
Subject(s)
Adenocarcinoma, Follicular/complications , Biopsy, Fine-Needle , Cytodiagnosis , Female , Forehead/pathology , Humans , Middle Aged , Neck/pathology , Scalp/pathology , Skin Neoplasms/secondary , Thyroid Neoplasms/complicationsABSTRACT
Pendred syndrome is a rare inherited disorder of bilateral sensorineural deafness with goitre. Presence of follicular carcinoma thyroid makes it even rarer. A case of a young girl is described with the features of Pendred syndrome and euthyroid state. Follicular carcinoma of thyroid was detected on histopathology requiring re-tailoring of the management
Subject(s)
Humans , Female , Thyroid Neoplasms/therapy , Adenocarcinoma, Follicular/complications , Goiter/complications , Hearing Loss, Sensorineural , Thyroidectomy , Syndrome , Thyroid DiseasesABSTRACT
Association of thyroid carcinoma in thyrotoxicosis is uncommon. Preoperative diagnosis of such association is difficult. In a retrospective study of 49 operated cases of Graves' disease (GD) such an association was found in four patients. Findings of a palpable nodule, calcification and a cold nodule on scanning in Graves' disease should increase suspicion for such an association and a frozen section study should be underken in all these cases during surgery to exclude possible co-existing malignancy.